The landscapes are stunning, and even without all the collateral activities (anacondas, sloths, dolphins, piranhas, indios etc.) it is in itself a must-see destination. Make sure to watch Werner Herzog’s Aguirre, one my favorite movies of all time, as you will be filming the same locations, and will expect to meet a raft of Spanish Conquistadores. Also, play Florian Fricke’s soundtrack on loop.